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“Our goal is to comprehend female reproductive growing old, and why fertility quickly declines beginning within the mid-30s,” claims Satoshi Namekawa, a professor of Microbiology and Molecular Genetics, in whose lab Munakata performs.
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Using the GCRLE grant, Munakata and Namekawa will glimpse more carefully at how oocytes are genomically primed and stored for later use. They may investigate the part of the chromatin remodeler in oocyte survival and fertility.
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In 2022, they discovered that a list of proteins known here as Polycomb repressive intricate one (PRC1) allows silence a huge selection of genes throughout the time of start by modifying the framework of spools.
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